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    Patient Profiles

    Name: John Age: 65
    Candidate for ORTHOVISC®
    Diagnosed 6 years ago. MRIMagnetic Resonance Imaging (MRI)
    A special imaging technique used to image internal structures of the body particularly the soft tissues
    findings show OA in the left knee
    History of heart disease with two years post-coronary stent
    Moderate Pain- Current activity level affected by stiffness, diminished range of motion, interferes with daily function and ability to maintain exercise regimen
    Previous Treatment
    • OTC NSAIDsNSAIDs
      A nonsteroidal anti-inflammatory drug such as ibuprofen
      — insufficient pain relief
    • IA corticosteroid injectionsCorticosteroid Injections
      A steroid hormone produced by the adrenal cortex (the outer portion of the adrenal glands); administered as drugs they reduce swelling and decrease the body's immune response
      - 4 in 3 years
    • Completed Physical Therapy
    • Total Joint ReplacementTotal Joint Replacement
      Repair of a damaged joint by replacing with a synthetic joint implant, made of either plastic, ceramic, titanium or stainless steel, in an effort to return normal function to affected joint
      discussed but not ready at this time
    Name: Jane Age: 58
    Candidate for ORTHOVISC®
    Diagnosed 4 years ago with OA in the left knee
    History of GastrointestinalGastrointestinal
    Relating to or affecting both stomach and intestine
      Issues
    Mild to Moderate Pain that interferes with daily function, stiffness, pain at night, range of motion- standing/bending
    Previous Treatment
    • OTC NSAIDs— adverse events
    • IA corticosteroid injections- 2 in 12 months
    • Completed Physical Therapy
    • Discussed Arthroscopic Intervention but did not want to proceed at this time
    Name: Tom Age: 42
    Candidate for ORTHOVISC®
    Diagnosed with degenerative condition of the knee 3 months ago
    History of previous athletic injuries, family history of diabetes and arthritis. Knee scopeKnee Scope
    Examination of a knee through an endoscope (an instrument for visualizing the interior of a hollow organ)
    3 months ago and continues to have pain post scope.
    Moderate Pain causing pain at rest, wake during sleeping, pain and stiffness in joints, noise in joint during movement
    Previous Treatment
    • Heat, ice, massage and topical medications
    • AcetaminophenAcetaminophen
      A drug used to relieve pain and fever
    • COX-2 InhibitorsCOX-2 Inhibitors
      Any of a class of nonsteroidal anti-inflammatory drugs to relieve the pain and inflammation of arthritis and thought to minimize gastrointestinal side effects
      — safety concern
    • IA corticosteriod injections 4 in 2 years
    • Physical therapy
    • Knee scope
    Name: Kathy Age: 50
    Candidate for ORTHOVISC®
    Diagnosed 5 years ago with OA of the knee
    History of obesity with dramatic weight loss occurring 7 years ago
    Moderate Pain causing crackling sensations and joint buckling which interfered with activities of daily living
    Previous Treatment
    • Heat, ice, acupuncture and dietary supplements
    • AcetaminophenAcetaminophen
      A drug used to relieve pain and fever
    • OTC NSAIDs— inadequate pain relief
    • COX-2 Inhibitors— effectiveness beginning to diminish
    • Physical therapy
    • IA corticosteroid injections 2 in 1 year
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