GLOSSARY OF ORTHOVISC®
- Acetaminophen
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A drug used to relieve pain and fever
Back to top - Acupuncture
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Originally a Chinese practice of inserting fine needles through the skin at specific points especially to cure disease or relieve pain
Back to top - Analgesics
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Agents for producing pain relief
Back to top - Arthralgia
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Pain in one or more joints
Back to top - Arthritis
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Inflammation of a joint or joints resulting in pain, swelling and stiffness
Back to top - Arthroplasty
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The operative formation or restoration of a joint
Back to top - Arthroscope
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An instrument for visualizing the interior of a hollow organ that is inserted through an incision near a joint (as the knee) and is used for the visual examination, diagnosis, and treatment of the interior of a joint
Back to top - Arthroscopy
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Examination of a joint with a scope
Back to top - Articular
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Of or relating to a joint
Back to top - Articular Cartilage
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Cartilage that covers the articular surfaces of bones
Back to top - Aseptic
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Freedom from infection, sterile
Back to top - Aspiration
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The withdrawal of fluid from the body
Back to top - Avian
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Derived from birds
Back to top - Buffers
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A substance or mixture of substances that in a solution tends to stabilize and neutralize, within limits, both acids and bases
Back to top - Cartilage
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A usually translucent somewhat elastic tissue that composes most of the skeleton
Back to top - Chronic Synovial Inflammation
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Inflammation of synovial fluid lasting for a long period of time or marked by frequent recurrence
Back to top - CMS
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Center for Medicare and Medicaid Services
Back to top - Co morbidities
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Occurring or existing concurrently but unrelated pathological or disease process
Back to top - Contraindicated
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To make a treatment or procedure inadvisable
Back to top - Contralateral
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Occurring on, affecting, or acting in conjunction with a part on the opposite side of the body
Back to top - Coronary Artery Bypass Graft (CABG)
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Open-heart surgery in which the rib cage is opened and a section of a blood vessel is grafted from the aorta to the coronary artery to bypass the blocked section of the coronary artery and improve the blood supply to the heart
Back to top - Corticosteroid Injections
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A steroid hormone produced by the adrenal cortex (the outer portion of the adrenal glands); administered as drugs they reduce swelling and decrease the body's immune response
Back to top - COX-2 Inhibitors
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Any of a class of nonsteroidal anti-inflammatory drugs to relieve the pain and inflammation of arthritis and thought to minimize gastrointestinal side effects
Back to top - Degenerative Arthritis/Degenerative Joint Disease
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Disease that leads to the gradual deterioration of a joint; also called Osteoarthritis.
Back to top - Efficacy
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Capacity for producing a desired result or effect
Back to top - Elastoviscous/Elastoviscosity
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And ideal viscosupplementation solution enhances elastic (high impact- such as running) and viscous (low impact- such as walking) properties in a knee with osteoarthritis
Back to top - Endorphins
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Any of a group of endogenous peptides that bind chiefly to opiate receptors (in the cell membrane) and produce some of the same pharmacological effects (pain relief) as those of opiates (dulls the senses and induces relaxation)
Back to top - Gastrointestinal
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Relating to or affecting both stomach and intestine
Back to top - Glucocorticoids (steroids)
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Any of a group of steroid hormones, such as cortisone, that are produced by the adrenal cortex (the outer portion of the adrenal glands) and have anti-inflammatory properties
Back to top - Homeostasis
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The maintenance of relatively stable internal physiological conditions such as body temperature or the pH of blood
Back to top - Hyaluronan/Hyaluronate
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A substance found naturally in joint fluid that acts as a shock absorber and lubricant in the knee joint and is necessary for the joint to function properly.
Back to top - Hyaluronic Acid
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A substance injected into a knee with osteoarthritis. Serves to restore lubrication and shock absorbing capabilities that have been depleted due to the disease of osteoarthritis.
Back to top - Immunogenic
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Relating to or producing an immune response
Back to top - Intraarticular Injections
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An injection administered by entering a joint
Back to top - Joint Aspiration
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The act of removing a fluid from a joint in the body by a hollow needle connected with a suction syringe
Back to top - Joint Fluid
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A transparent, lubricating fluid secreted by a membrane of an articulation (place of union between two or more joints) or bursa (a saclike body cavity between a tendon and bone)
Back to top - Knee Scope
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Examination of a knee through an endoscope (an instrument for visualizing the interior of a hollow organ)
Back to top - Magnetic Resonance Imaging (MRI)
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A special imaging technique used to image internal structures of the body particularly the soft tissues
Back to top - Molecular Weight
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The sum of the atomic weights of all the atoms in a molecule
Back to top - Nonpharmacologic Therapy
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A non-drug therapy, such as exercise, with therapeutic value
Back to top - NSAIDs
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A nonsteroidal anti-inflammatory drug such as ibuprofen
Back to top - ORTHOVISC®
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Ultra-pure natural hyaluronan that is injected intraarticular into the knee and is indicated in the treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and to simple analgesics
Back to top - Osteoarthritis
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Arthritis typically with onset during middle or old age that is characterized by degenerative (gradual deterioration of joint) and sometimes abnormal growth in the bone and cartilage of one or more joints and a progressive wearing down of opposing joint surfaces with consequent distortion of joint position and is marked symptomatically especially by pain, swelling, and stiffness; abbreviation (OA)
Back to top - Osteophyte
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A bony outgrowth
Back to top - Physiologic Saline
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An approximately 0.9 percent solution of sodium chloride; also called normal saline solution
Back to top - Physiotherapy
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A therapy that uses physical agents such as exercise, massage and other modalities
Back to top - Placebo
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An inert substance used especially in controlled experiments testing the efficacy of another substance such as a drug
Back to top - Preservatives
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Something that preserves or has the power of preserving
Back to top - Pseudoseptic reaction reported
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Severe inflammation of the joint often with significant pain normally occurring 24 to 72 hours after intraarticular injection; often requires clinical intervention
Back to top - Rheologic
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Of or relating to the phenomena of flowing matter
Back to top - Spurs
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A sharp, bony outgrowth located at the end of a bone
Back to top - subchondral
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Situated beneath cartilage
Back to top - Synovial Fluid
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A lubricating fluid resembling the white of an egg, secreted by certain membranes, as those of the joints; also called joint fluid
Back to top - Synovium
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The inner membrane of a joint capsule surrounding a freely movable joint.
Back to top - Total Joint Replacement
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Repair of a damaged joint by replacing with a synthetic joint implant, made of either plastic, ceramic, titanium or stainless steel, in an effort to return normal function to affected joint
Back to top - Viscoelasticity
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Having the quality of being thick and slow-flowing
Back to top - Viscosity
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The property of resistance to flow in a fluid
Back to top - Viscosupplementation Injections
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A procedure that replaces diseased synovial fluid in people with osteoarthritis of the knee in an effort to decrease pain, enhance range of motion and increase joint mobility
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