HA is an important component of synovial fluid.
High concentration and high molecular
weight ORTHOVISC® closely matches
healthy synovial fluid. It provides safe
and lasting pain relief with no
reports of pseudoseptic reactions4.
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This site is published by DePuy Mitek, Inc., which is solely responsible for its contents.
It is intended for healthcare professionals in the U.S. and contains U.S. based product information only.
ORTHOVISC® is manufactured by and is a registered trademark of Anika Therapeutics, Inc. Distributed by DePuy Mitek, Inc.
© DePuy Mitek, Inc. 2005 - 2014
ORTHOVISC® is indicated in the treatment of pain in osteoarthritis (OA) of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy and to simple analgesics, e.g. acetaminophen. In clinical studies, the most commonly reported adverse events were arthralgia, back pain, and headache. Other side effects included local injection site adverse events.
ORTHOVISC® is contraindicated in patients with known hypersensitivity to hyaluronate formulations or known hypersensitivity (allergy) to gram positive bacterial proteins. ORTHOVISC® should not be injected in patients with infections or skin diseases in the area of the injection site or joint. Strict aseptic technique should be used. The effectiveness of more than 1 course has not been established.